Human CD32b / FCGR2B Protein (His & AVI Tag), Biotinylated 10259-H27H-B from Sino Biological, Inc.

Product Specs
ItemHuman CD32b / FCGR2B Protein (His & AVI Tag), Biotinylated
CompanySino Biological, Inc.
Price Supplier Page View Company Product Page
Catalog Number10259-H27H-B
Conjugate/TagC-AVI, His
Purity> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant mature human CD32b consists of 214 amino acids after proteolytic removal of the signal peptide and predicts a molecular mass of 24 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of the protein is approximately 35 kDa protein due to glycosylation
SpeciesHuman
Molecule NameFCGR2B
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameFc gamma receptor IIb
NCBI Gene AliasesCD32, CD32B, FCG2, FCGR2, FCGR2C, FcGRIIB, FcRII-c, FcgammaRIIb, IGFR2
ActivityLoaded Biotinylated Human FcγRIIB/C / CD32b/c protein (His & Avi Tag) (Cat. 10259-H27H-B) on SA Biosensor, can bind Bevacizumab (IgG1) with an affinity constant of 1.2 µM as determined in a BLI assay (Sartorius Octet Red384) (QC tested)
FormatLyophilized from sterile PBS, pH 7.4

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Sino Biological, Inc.

1400 Liberty Ridge Drive

Suite 101

Wayne, PA 19087

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: http://www.sinobiological.com/

(1) C-Reactive Protein Enhances IgG-Mediated Cellular Destruction Through IgG-Fc Receptors in vitroFrontiers in ImmunologyMarch 15, 2021A. Robin Temming et al.,Sino Biological,S FcγRIIa-H131,Biotin,N.A.,10374-H27H1-B,Sino Biological,S FcγRIIa-R131,Biotin,N.A.,10374-H27H-B,Sino Biological,S FcγRIIb,Biotin,N.A.,10259-H27H-B,Sino Biological,S FcγRIIIa-V158,Biotin,N.A.,10389-H27H1-B,Sino Biological,S FcγRIIIa-F158,Biotin,N.A.,10389-H27H-B,Sino Biological

(2) Cross-reactivity of mouse IgG subclasses to human Fc gamma receptors: Antibody deglycosylation only eliminates IgG2b bindingMolecular immunologyNovember 1, 2020Temming AR, Bentlage AEH, de Taeye SW, Bosman GP, Lissenberg-Thunnissen SN, Derksen NIL, Brasser G, Mok JY, van Esch WJE, Howie HL, et al.

(3) FcγR Binding and ADCC Activity of Human IgG AllotypesFrontiers in immunologyJanuary 1, 2020de Taeye SW, Bentlage AEH, Mebius MM, Meesters JI, Lissenberg-Thunnissen S, Falck D, Sénard T, Salehi N, Wuhrer M, Schuurman J, et al.(131His, biotinylated, 10374-H27H1-B-50 and 131Arg, biotinylated, 10374-H27H-B-50), FcγRIIb (biotinylated, 10259-H27H-B-50), and FcγRIIIa (158Phe, biotinylated, 10389-H27H-B-50, and 158Val, biotinylated, 10389-H27H1-B-50)

(4) Enhanced Effector Functions Due to Antibody Defucosylation Depend on the Effector Cell Fcγ Receptor ProfileJournal of immunology (Baltimore, Md. : 1950)July 1, 2017Bruggeman CW, Dekkers G, Bentlage AEH, Treffers LW, Nagelkerke SQ, Lissenberg-Thunnissen S, Koeleman CAM, Wuhrer M, van den Berg TK, Rispens T, et al.FcgRIIa (131His, biotinylated, 10374-H27H1-B-50 and 131Arg, biotinylated, 10374H27H-B-50), FcgRIIb (biotinylated, 10259-H27H-B-50), and FcgRIIIa (158Phe, biotinylated, 10389-H27H-B-50, and 158Val, biotinylated, 10389H27H1-B-50)

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Human CD32b / FCGR2B Protein (His & AVI Tag), Biotinylated

Human CD32b / FCGR2B Protein (His & AVI Tag), Biotinylated from Sino Biological, Inc.

Description

Sino Biological, Inc.

Citations (4)

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Human CD32b / FCGR2B Protein (His & AVI Tag), Biotinylated from Sino Biological, Inc.

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